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PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

PTEN is a critical tumour suppressor that is frequently mutated in human cancer. We have previously identified a CUG initiated PTEN isoform designated PTENα, which functions in mitochondrial bioenergetics. Here we report the identification of another N-terminal extended PTEN isoform, designated PTEN...

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Detalles Bibliográficos
Autores principales: Liang, Hui, Chen, Xi, Yin, Qi, Ruan, Danhui, Zhao, Xuyang, Zhang, Cong, McNutt, Michael A., Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376652/
https://www.ncbi.nlm.nih.gov/pubmed/28332494
http://dx.doi.org/10.1038/ncomms14771