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Functional implications of Neandertal introgression in modern humans

BACKGROUND: Admixture between early modern humans and Neandertals approximately 50,000–60,000 years ago has resulted in 1.5–4% Neandertal ancestry in the genomes of present-day non-Africans. Evidence is accumulating that some of these archaic alleles are advantageous for modern humans, while others...

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Detalles Bibliográficos
Autores principales: Dannemann, Michael, Prüfer, Kay, Kelso, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376702/
https://www.ncbi.nlm.nih.gov/pubmed/28366169
http://dx.doi.org/10.1186/s13059-017-1181-7