The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes

A mild palladium-catalyzed ligand-controlled regioselective 1,3-arylfluorination of 2[H]-chromenes has been developed. The products with a syn-1,3 substitution pattern were obtained with high enantiomeric excess using a PyrOx ligand, wherein the utility of these pyranyl-fluorides was further demonst...

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Detalles Bibliográficos
Autores principales: Thornbury, Richard T., Saini, Vaneet, Fernandes, Talita de A., Santiago, Celine B., Talbot, Eric P. A., Sigman, Matthew S., McKenna, Jeffrey M., Toste, F. Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376715/
https://www.ncbi.nlm.nih.gov/pubmed/28451354
http://dx.doi.org/10.1039/c6sc05102b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376715/
https://www.ncbi.nlm.nih.gov/pubmed/28451354
http://dx.doi.org/10.1039/c6sc05102b

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