Osteopontin attenuates aging‐associated phenotypes of hematopoietic stem cells

Upon aging, hematopoietic stem cells (HSCs) undergo changes in function and structure, including skewing to myeloid lineages, lower reconstitution potential and loss of protein polarity. While stem cell intrinsic mechanisms are known to contribute to HSC aging, little is known on whether age‐related...

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Detalles Bibliográficos
Autores principales: Guidi, Novella, Sacma, Mehmet, Ständker, Ludger, Soller, Karin, Marka, Gina, Eiwen, Karina, Weiss, Johannes M, Kirchhoff, Frank, Weil, Tanja, Cancelas, Jose A, Florian, Maria Carolina, Geiger, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376966/
https://www.ncbi.nlm.nih.gov/pubmed/28254837
http://dx.doi.org/10.15252/embj.201694969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376966/
https://www.ncbi.nlm.nih.gov/pubmed/28254837
http://dx.doi.org/10.15252/embj.201694969

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