Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain

VAR2CSA stands today as the leading vaccine candidate aiming to protect future pregnant women living in malaria endemic areas against the severe clinical outcomes of pregnancy associated malaria (PAM). The rational design of an efficient VAR2CSA-based vaccine relies on a profound understanding of th...

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Detalles Bibliográficos
Autores principales: Nunes-Silva, Sofia, Gangnard, Stéphane, Vidal, Marta, Vuchelen, Anneleen, Dechavanne, Sebastien, Chan, Sherwin, Pardon, Els, Steyaert, Jan, Ramboarina, Stephanie, Chêne, Arnaud, Gamain, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376981/
https://www.ncbi.nlm.nih.gov/pubmed/25487735
http://dx.doi.org/10.1038/srep07373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376981/
https://www.ncbi.nlm.nih.gov/pubmed/25487735
http://dx.doi.org/10.1038/srep07373

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