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Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain
VAR2CSA stands today as the leading vaccine candidate aiming to protect future pregnant women living in malaria endemic areas against the severe clinical outcomes of pregnancy associated malaria (PAM). The rational design of an efficient VAR2CSA-based vaccine relies on a profound understanding of th...
Autores principales: | Nunes-Silva, Sofia, Gangnard, Stéphane, Vidal, Marta, Vuchelen, Anneleen, Dechavanne, Sebastien, Chan, Sherwin, Pardon, Els, Steyaert, Jan, Ramboarina, Stephanie, Chêne, Arnaud, Gamain, Benoît |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376981/ https://www.ncbi.nlm.nih.gov/pubmed/25487735 http://dx.doi.org/10.1038/srep07373 |
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