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Electrophysiological, behavioral and histological characterization of paclitaxel, cisplatin, vincristine and bortezomib-induced neuropathy in C57Bl/6 mice

Polyneuropathy is a frequent and potentially severe side effect of clinical tumor chemotherapy. The goal of this study was to characterize paclitaxel-, cisplatin-, vincristine- and bortezomib-induced neuropathy in C57BL/6 mice with a comparative approach. The phenotype of the animals was evaluated a...

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Detalles Bibliográficos
Autores principales: Boehmerle, Wolfgang, Huehnchen, Petra, Peruzzaro, Sarah, Balkaya, Mustafa, Endres, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377307/
https://www.ncbi.nlm.nih.gov/pubmed/25231679
http://dx.doi.org/10.1038/srep06370