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Generation of Aptamers from A Primer-Free Randomized ssDNA Library Using Magnetic-Assisted Rapid Aptamer Selection

Aptamers are oligonucleotides that can bind to specific target molecules. Most aptamers are generated using random libraries in the standard systematic evolution of ligands by exponential enrichment (SELEX). Each random library contains oligonucleotides with a randomized central region and two fixed...

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Detalles Bibliográficos
Autores principales: Tsao, Shih-Ming, Lai, Ji-Ching, Horng, Horng-Er, Liu, Tu-Chen, Hong, Chin-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377317/
https://www.ncbi.nlm.nih.gov/pubmed/28367958
http://dx.doi.org/10.1038/srep45478