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Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen assembly. Our aim was to investigate the role of fibromodulin in healthy and fibrotic lung parenchyma, theorizing that fib...

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Detalles Bibliográficos
Autores principales: Rydell-Törmänen, Kristina, Andréasson, Kristofer, Hesselstrand, Roger, Westergren-Thorsson, Gunilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377322/
https://www.ncbi.nlm.nih.gov/pubmed/25230586
http://dx.doi.org/10.1038/srep06383