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Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma
The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen assembly. Our aim was to investigate the role of fibromodulin in healthy and fibrotic lung parenchyma, theorizing that fib...
Autores principales: | Rydell-Törmänen, Kristina, Andréasson, Kristofer, Hesselstrand, Roger, Westergren-Thorsson, Gunilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377322/ https://www.ncbi.nlm.nih.gov/pubmed/25230586 http://dx.doi.org/10.1038/srep06383 |
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