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Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway

The extracellular signals induced by vascular endothelial growth factor (VEGF) are implicated in choroidal neovascularization (CNV) and thus, are associated with vision-limiting complications in the human retina. Vandetanib is an oral anticancer drug that selectively inhibits the activities of VEGF...

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Detalles Bibliográficos
Autores principales: Kim, Daejin, Ko, Hyun-Suk, Park, Ga Bin, Hur, Dae Young, Kim, Yeong Seok, Yang, Jae Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377331/
https://www.ncbi.nlm.nih.gov/pubmed/28413487
http://dx.doi.org/10.3892/etm.2017.4110