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Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway
The extracellular signals induced by vascular endothelial growth factor (VEGF) are implicated in choroidal neovascularization (CNV) and thus, are associated with vision-limiting complications in the human retina. Vandetanib is an oral anticancer drug that selectively inhibits the activities of VEGF...
Autores principales: | Kim, Daejin, Ko, Hyun-Suk, Park, Ga Bin, Hur, Dae Young, Kim, Yeong Seok, Yang, Jae Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377331/ https://www.ncbi.nlm.nih.gov/pubmed/28413487 http://dx.doi.org/10.3892/etm.2017.4110 |
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