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Icariin improves osteoporosis, inhibits the expression of PPARγ, C/EBPα, FABP4 mRNA, N1ICD and jagged1 proteins, and increases Notch2 mRNA in ovariectomized rats

Icariin (ICA) is a pharmacologically active flavonoid glycoside that shows promise in the treatment and prevention of osteoporosis (OP). However, the mechanisms underlying the anti-osteoporotic effects of ICA remain largely unclear. The present study used quantitative polymerase chain reaction, west...

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Detalles Bibliográficos
Autores principales: Liu, Hengrui, Xiong, Yingquan, Zhu, Xiaofeng, Gao, Han, Yin, Sujuan, Wang, Jiefang, Chen, Guangming, Wang, Chaopeng, Xiang, Lu, Wang, Panpan, Fang, Ji, Zhang, Ronghua, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377361/
https://www.ncbi.nlm.nih.gov/pubmed/28413478
http://dx.doi.org/10.3892/etm.2017.4128