Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer’s-like memory deficits in the Ts65Dn mouse model of Down syndrome

Down syndrome (DS), caused by trisomy 21, is the most common genetic cause of intellectual disability and is associated with a greatly increased risk of early-onset Alzheimer’s disease (AD). The Ts65Dn mouse model of DS exhibits several key features of the disease including developmental delay and A...

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Detalles Bibliográficos
Autores principales: Kazim, Syed Faraz, Blanchard, Julie, Bianchi, Riccardo, Iqbal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377379/
https://www.ncbi.nlm.nih.gov/pubmed/28368015
http://dx.doi.org/10.1038/srep45561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377379/
https://www.ncbi.nlm.nih.gov/pubmed/28368015
http://dx.doi.org/10.1038/srep45561

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