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Suppression of muscle wasting by the plant‐derived compound ursolic acid in a model of chronic kidney disease

BACKGROUND: Muscle wasting in chronic kidney disease (CKD) and other catabolic disorders contributes to morbidity and mortality, and there are no therapeutic interventions that regularly and safely block losses of muscle mass. We have obtained evidence that impaired IGF‐1/insulin signalling and incr...

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Detalles Bibliográficos
Autores principales: Yu, Rizhen, Chen, Ji‐an, Xu, Jing, Cao, Jin, Wang, Yanlin, Thomas, Sandhya S., Hu, Zhaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377392/
https://www.ncbi.nlm.nih.gov/pubmed/27897418
http://dx.doi.org/10.1002/jcsm.12162