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Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma

Smad ubiquitin regulatory factor 1 (SMURF1), a recently identified E3 ubiquitin ligase, targets substrate proteins for ubiquitination and proteasomal degradation. Previous studies have reported that SMURF1 also functions as an oncogene in human cancers. However, the clinical value of SMURF1 and its...

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Detalles Bibliográficos
Autores principales: Ke, Mang, Mo, Licai, Li, Weilin, Zhang, Xianjun, Li, Feiping, Yu, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377408/
https://www.ncbi.nlm.nih.gov/pubmed/28396841
http://dx.doi.org/10.1002/2211-5463.12204