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Multifunctional Enveloped Mesoporous Silica Nanoparticles for Subcellular Co-delivery of Drug and Therapeutic Peptide

A multifunctional enveloped nanodevice based on mesoporous silica nanoparticle (MSN) was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor cells. Mesoporous silica MCM-41 nanoparticles were used as the core for loading antineoplastic drug topotecan (TPT). The s...

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Detalles Bibliográficos
Autores principales: Luo, Guo-Feng, Chen, Wei-Hai, Liu, Yun, Lei, Qi, Zhuo, Ren-Xi, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377537/
https://www.ncbi.nlm.nih.gov/pubmed/25317538
http://dx.doi.org/10.1038/srep06064