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Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing

There is a need for new interventions against the ongoing burden of vector-borne diseases such as malaria and dengue. One suggestion has been to develop genes encoding effector molecules that block parasite development within the vector, and then use the nuclease-based homing reaction as a form of g...

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Detalles Bibliográficos
Autores principales: Beaghton, Andrea, Hammond, Andrew, Nolan, Tony, Crisanti, Andrea, Godfray, H. Charles J., Burt, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378115/
https://www.ncbi.nlm.nih.gov/pubmed/28159753
http://dx.doi.org/10.1534/genetics.116.197632