Functional identification of islet cell types by electrophysiological fingerprinting

The α-, β- and δ-cells of the pancreatic islet exhibit different electrophysiological features. We used a large dataset of whole-cell patch-clamp recordings from cells in intact mouse islets (N = 288 recordings) to investigate whether it is possible to reliably identify cell type (α, β or δ) based o...

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Detalles Bibliográficos
Autores principales: Briant, Linford J. B., Zhang, Quan, Vergari, Elisa, Kellard, Joely A., Rodriguez, Blanca, Ashcroft, Frances M., Rorsman, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Life Sciences–Mathematics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378133/
https://www.ncbi.nlm.nih.gov/pubmed/28275121
http://dx.doi.org/10.1098/rsif.2016.0999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378133/
https://www.ncbi.nlm.nih.gov/pubmed/28275121
http://dx.doi.org/10.1098/rsif.2016.0999

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