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Time-dependent genetic effects on gene expression implicate aging processes

Gene expression is dependent on genetic and environmental factors. In the last decade, a large body of research has significantly improved our understanding of the genetic architecture of gene expression. However, it remains unclear whether genetic effects on gene expression remain stable over time....

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Detalles Bibliográficos
Autores principales: Bryois, Julien, Buil, Alfonso, Ferreira, Pedro G., Panousis, Nikolaos I., Brown, Andrew A., Viñuela, Ana, Planchon, Alexandra, Bielser, Deborah, Small, Kerrin, Spector, Tim, Dermitzakis, Emmanouil T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378173/
https://www.ncbi.nlm.nih.gov/pubmed/28302734
http://dx.doi.org/10.1101/gr.207688.116