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Large-scale analysis of branchpoint usage across species and cell lines

The coding sequence of each human pre-mRNA is interrupted, on average, by 11 introns that must be spliced out for proper gene expression. Each intron contains three obligate signals: a 5′ splice site, a branch site, and a 3′ splice site. Splice site usage has been mapped exhaustively across differen...

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Detalles Bibliográficos
Autores principales: Taggart, Allison J., Lin, Chien-Ling, Shrestha, Barsha, Heintzelman, Claire, Kim, Seongwon, Fairbrother, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378181/
https://www.ncbi.nlm.nih.gov/pubmed/28119336
http://dx.doi.org/10.1101/gr.202820.115