Cargando…
Large-scale analysis of branchpoint usage across species and cell lines
The coding sequence of each human pre-mRNA is interrupted, on average, by 11 introns that must be spliced out for proper gene expression. Each intron contains three obligate signals: a 5′ splice site, a branch site, and a 3′ splice site. Splice site usage has been mapped exhaustively across differen...
Autores principales: | Taggart, Allison J., Lin, Chien-Ling, Shrestha, Barsha, Heintzelman, Claire, Kim, Seongwon, Fairbrother, William G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378181/ https://www.ncbi.nlm.nih.gov/pubmed/28119336 http://dx.doi.org/10.1101/gr.202820.115 |
Ejemplares similares
-
Genome-wide discovery of human splicing branchpoints
por: Mercer, Tim R., et al.
Publicado: (2015) -
Most human introns are recognized via multiple and tissue-specific branchpoints
por: Pineda, Jose Mario Bello, et al.
Publicado: (2018) -
Widespread intra-dependencies in the removal of introns from human transcripts
por: Kim, Seong Won, et al.
Publicado: (2017) -
Large‐scale across species transcriptomic analysis identifies genetic selection signatures associated with longevity in mammals
por: Liu, Weiqiang, et al.
Publicado: (2023) -
Dynamic DNA methylation across diverse human cell lines and tissues
por: Varley, Katherine E., et al.
Publicado: (2013)