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Targeting human vasohibin‐2 by a neutralizing monoclonal antibody for anti‐cancer treatment

There are two members of the vasohibin (VASH) family, VASH1 and VASH2. VASH1 is expressed mainly in endothelial cells to inhibit angiogenesis, whereas VASH2 is expressed mainly in cancer cells to stimulate tumor growth. The aim of the present study was to establish neutralizing monoclonal antibody (...

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Detalles Bibliográficos
Autores principales: Koyanagi, Takahiro, Suzuki, Yasuhiro, Komori, Kazuki, Saga, Yasushi, Matsubara, Shigeki, Fujiwara, Hiroyuki, Sato, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378258/
https://www.ncbi.nlm.nih.gov/pubmed/28032401
http://dx.doi.org/10.1111/cas.13149