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Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP‐TEAD complex

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The Yes‐associated protein‐1 (YAP) plays a critical role in cell proliferation, apoptosis and angiogenesis. Verteporfin is a photosensitizer used in photodynamic therapy and also a small molecular inhibitor of...

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Detalles Bibliográficos
Autores principales: Wei, Honglong, Wang, Fuhai, Wang, Yong, Li, Tao, Xiu, Peng, Zhong, Jingtao, Sun, Xueying, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378285/
https://www.ncbi.nlm.nih.gov/pubmed/28002618
http://dx.doi.org/10.1111/cas.13138