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Tannerella forsythia strains display different cell-surface nonulosonic acids: biosynthetic pathway characterization and first insight into biological implications

Tannerella forsythia is an anaerobic, Gram-negative periodontal pathogen. A unique O-linked oligosaccharide decorates the bacterium's cell surface proteins and was shown to modulate the host immune response. In our study, we investigated the biosynthesis of the nonulosonic acid (NulO) present a...

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Detalles Bibliográficos
Autores principales: Friedrich, Valentin, Janesch, Bettina, Windwarder, Markus, Maresch, Daniel, Braun, Matthias L, Megson, Zoë A, Vinogradov, Evgeny, Goneau, Marie-France, Sharma, Ashu, Altmann, Friedrich, Messner, Paul, Schoenhofen, Ian C, Schäffer, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378307/
https://www.ncbi.nlm.nih.gov/pubmed/27986835
http://dx.doi.org/10.1093/glycob/cww129