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Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein

Proteins evolve through two primary mechanisms: substitution, where mutations alter a protein’s amino-acid sequence, and insertions and deletions (indels), where amino acids are either added to or removed from the sequence. Protein structure has been shown to influence the rate at which substitution...

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Detalles Bibliográficos
Autores principales: Jackson, Eleisha L., Spielman, Stephanie J., Wilke, Claus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378326/
https://www.ncbi.nlm.nih.gov/pubmed/28369116
http://dx.doi.org/10.1371/journal.pone.0164905