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Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein
Proteins evolve through two primary mechanisms: substitution, where mutations alter a protein’s amino-acid sequence, and insertions and deletions (indels), where amino acids are either added to or removed from the sequence. Protein structure has been shown to influence the rate at which substitution...
Autores principales: | Jackson, Eleisha L., Spielman, Stephanie J., Wilke, Claus O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378326/ https://www.ncbi.nlm.nih.gov/pubmed/28369116 http://dx.doi.org/10.1371/journal.pone.0164905 |
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