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Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson’s disease

Parkinson's disease (PD) is a neurodegenerative disease in which degeneration of nigrostriatal neurons and inflammation are key players. The aim of our study was to analyze the function of LXRs in neurodegenerative diseases as PD using in vivo, ex vivo and in vitro models of PD; for this purpos...

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Detalles Bibliográficos
Autores principales: Paterniti, Irene, Campolo, Michela, Siracusa, Rosalba, Cordaro, Marika, Di Paola, Rosanna, Calabrese, Vittorio, Navarra, Michele, Cuzzocrea, Salvatore, Esposito, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378346/
https://www.ncbi.nlm.nih.gov/pubmed/28369131
http://dx.doi.org/10.1371/journal.pone.0174470