A computational analysis of in vivo VEGFR activation by multiple co-expressed ligands

The splice isoforms of vascular endothelial growth A (VEGF) each have different affinities for the extracellular matrix (ECM) and the coreceptor NRP1, which leads to distinct vascular phenotypes in model systems expressing only a single VEGF isoform. ECM-immobilized VEGF can bind to and activate VEG...

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Detalles Bibliográficos
Autores principales: Clegg, Lindsay E., Mac Gabhann, Feilim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378411/
https://www.ncbi.nlm.nih.gov/pubmed/28319199
http://dx.doi.org/10.1371/journal.pcbi.1005445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378411/
https://www.ncbi.nlm.nih.gov/pubmed/28319199
http://dx.doi.org/10.1371/journal.pcbi.1005445

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