Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

The major obstacle to curing HIV infection is the persistence of cells with intact proviruses that can produce replication-competent virus. This HIV reservoir is believed to exist primarily in CD4(+) T-cells and is stable despite years of suppressive antiretroviral therapy. A potential mechanism for...

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Detalles Bibliográficos
Autores principales: Bui, John K., Sobolewski, Michele D., Keele, Brandon F., Spindler, Jonathan, Musick, Andrew, Wiegand, Ann, Luke, Brian T., Shao, Wei, Hughes, Stephen H., Coffin, John M., Kearney, Mary F., Mellors, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378418/
https://www.ncbi.nlm.nih.gov/pubmed/28328934
http://dx.doi.org/10.1371/journal.ppat.1006283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378418/
https://www.ncbi.nlm.nih.gov/pubmed/28328934
http://dx.doi.org/10.1371/journal.ppat.1006283

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