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Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice

Mitogen-activated protein kinase (MAPK) phosphatase-3 (MKP-3) and its substrates (extracellular signal-regulated kinase [ERK] and p38) play an important role in pathophysiological mechanisms of acute postoperative and chronic neuropathic pain in the spinal cord. This study aimed to understand the ro...

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Detalles Bibliográficos
Autores principales: Skopelja-Gardner, Sladjana, Saha, Madhurima, Alvarado-Vazquez, Perla Abigail, Liponis, Brenna S, Martinez, Elena, Romero-Sandoval, E Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378457/
https://www.ncbi.nlm.nih.gov/pubmed/28405172
http://dx.doi.org/10.2147/JPR.S129826