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Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system

As a potent therapeutic agent, small interfering RNA (siRNA) has been exploited to silence critical genes involved in tumor initiation and progression. However, development of a desirable delivery system is required to overcome the unfavorable properties of siRNA such as its high degradability, mole...

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Detalles Bibliográficos
Autores principales: Xiang, Bai, Jia, Xue-Li, Qi, Jin-Long, Yang, Li-Ping, Sun, Wei-Hong, Yan, Xiao, Yang, Shao-Kun, Cao, De-Ying, Du, Qing, Qi, Xian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378471/
https://www.ncbi.nlm.nih.gov/pubmed/28405163
http://dx.doi.org/10.2147/IJN.S129574