Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells

PURPOSE: Tumor cells have increased turnover of nicotinamide adenine dinucleotide (NAD(+)), the main coenzyme in processes including adenosine diphosphate-ribosylation, deacetylation, and calcium mobilization. NAD(+) is predominantly synthesized in human cells via the salvage pathway, with the first...

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Detalles Bibliográficos
Autores principales: Alaee, Mohammad, Khaghani, Shahnaz, Behroozfar, Kiarash, Hesari, Zahra, Ghorbanhosseini, Seyedeh Sara, Nourbakhsh, Mitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378576/
https://www.ncbi.nlm.nih.gov/pubmed/28382091
http://dx.doi.org/10.4048/jbc.2017.20.1.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378576/
https://www.ncbi.nlm.nih.gov/pubmed/28382091
http://dx.doi.org/10.4048/jbc.2017.20.1.20

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