ZEB1 Induces LOXL2-Mediated Collagen Stabilization and Deposition in the Extracellular Matrix to Drive Lung Cancer Invasion and Metastasis

Lung cancer is the leading cause of cancer-related death, primarily due to distant metastatic disease. Metastatic lung cancer cells can undergo an epithelial-to-mesenchymal transition (EMT) regulated by many transcription factors, including double-negative feedback loop between the microRNA-200 (miR...

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Detalles Bibliográficos
Autores principales: Peng, David H., Ungewiss, Christin, Tong, Pan, Byers, Lauren A., Wang, Jing, Canales, Jaime Rodriguez, Villalobos, Pamela A., Uraoka, Naohiro, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio I., Han, Richard I, Wanna, Charles A., Fahrenholtz, Monica, Grande-Allen, Kathryn Jane, Creighton, Chad J., Gibbons, Don L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378666/
https://www.ncbi.nlm.nih.gov/pubmed/27694892
http://dx.doi.org/10.1038/onc.2016.358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378666/
https://www.ncbi.nlm.nih.gov/pubmed/27694892
http://dx.doi.org/10.1038/onc.2016.358

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