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Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming

Tumor cells reprogram their metabolism to survive and grow in a challenging microenvironment. Some of this reprogramming is performed by epigenetic mechanisms. Epigenetics is in turn affected by metabolism; chromatin modifying enzymes are dependent on substrates that are also key metabolic intermedi...

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Detalles Bibliográficos
Autores principales: Nickerson, Jeffrey A., Wu, Qiong, Imbalzano, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378717/
https://www.ncbi.nlm.nih.gov/pubmed/28421159
http://dx.doi.org/10.3389/fonc.2017.00049