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The Proteasomal ATPases Use a Slow but Highly Processive Strategy to Unfold Proteins
All domains of life have ATP-dependent compartmentalized proteases that sequester their peptidase sites on their interior. ATPase complexes will often associate with these compartmentalized proteases in order to unfold and inject substrates into the protease for degradation. Significant effort has b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378721/ https://www.ncbi.nlm.nih.gov/pubmed/28421184 http://dx.doi.org/10.3389/fmolb.2017.00018 |