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Clinical features and viral quasispecies characteristics associated with infection by the hepatitis B virus G145R immune escape mutant

Coexistence of the hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is an uncommon phenomenon, and the underlying mechanisms remain largely unknown. Amino-acid (aa) substitution from glycine to arginine at aa 145 (G145R), in the major hydrophilic region, has been repor...

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Detalles Bibliográficos
Autores principales: Xue, Yuan, Wang, Ming-Jie, Yang, Zhi-Tao, Yu, De-Min, Han, Yue, Huang, Dao, Zhang, Dong-Hua, Zhang, Xin-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378923/
https://www.ncbi.nlm.nih.gov/pubmed/28325923
http://dx.doi.org/10.1038/emi.2017.2