Mapping sites of aspirin-induced acetylations in live cells by quantitative acid-cleavable activity-based protein profiling (QA-ABPP)

Target-identification and understanding of mechanism-of-action (MOA) are challenging for development of small-molecule probes and their application in biology and drug discovery. For example, although aspirin has been widely used for more than 100 years, its molecular targets have not been fully cha...

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Detalles Bibliográficos
Autores principales: Wang, Jigang, Zhang, Chong-Jing, Zhang, Jianbin, He, Yingke, Lee, Yew Mun, Chen, Songbi, Lim, Teck Kwang, Ng, Shukie, Shen, Han-Ming, Lin, Qingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379034/
https://www.ncbi.nlm.nih.gov/pubmed/25600173
http://dx.doi.org/10.1038/srep07896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379034/
https://www.ncbi.nlm.nih.gov/pubmed/25600173
http://dx.doi.org/10.1038/srep07896

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