Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K

Collective cell migration plays a crucial role in several biological processes, such as embryonic development, wound healing, and cancer metastasis. Here, we focused on collectively migrating Madin-Darby Canine Kidney (MDCK) epithelial cells that follow a leader cell on a collagen gel to clarify the...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Naoya, Mizutani, Takeomi, Kawabata, Kazushige, Haga, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379035/
https://www.ncbi.nlm.nih.gov/pubmed/25563751
http://dx.doi.org/10.1038/srep07656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379035/
https://www.ncbi.nlm.nih.gov/pubmed/25563751
http://dx.doi.org/10.1038/srep07656

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