Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death

Rifampicin, which inhibits bacterial RNA polymerase, provides one of the most effective treatments for tuberculosis. Inhibition of the transcription termination factor Rho is used to treat some bacterial infections, but its importance varies across bacteria. Here we show that Rho of Mycobacterium tu...

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Detalles Bibliográficos
Autores principales: Botella, Laure, Vaubourgeix, Julien, Livny, Jonathan, Schnappinger, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379054/
https://www.ncbi.nlm.nih.gov/pubmed/28348398
http://dx.doi.org/10.1038/ncomms14731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379054/
https://www.ncbi.nlm.nih.gov/pubmed/28348398
http://dx.doi.org/10.1038/ncomms14731

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