FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Here we report that FUS controls back-splicing reactions leading to circular RNA (circRNA) production. We identif...

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Detalles Bibliográficos
Autores principales: Errichelli, Lorenzo, Dini Modigliani, Stefano, Laneve, Pietro, Colantoni, Alessio, Legnini, Ivano, Capauto, Davide, Rosa, Alessandro, De Santis, Riccardo, Scarfò, Rebecca, Peruzzi, Giovanna, Lu, Lei, Caffarelli, Elisa, Shneider, Neil A., Morlando, Mariangela, Bozzoni, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379105/
https://www.ncbi.nlm.nih.gov/pubmed/28358055
http://dx.doi.org/10.1038/ncomms14741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379105/
https://www.ncbi.nlm.nih.gov/pubmed/28358055
http://dx.doi.org/10.1038/ncomms14741

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