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Study of the cytotoxic effects of 2,5-diaziridinyl-3,6-dimethyl-1,4-benzoquinone (MeDZQ) in mouse hepatoma cells

A number of quinones have been shown to be efficient anticancer agents. However, some mechanisms of their action, in particular cell signaling are not well understood. The aim of this study was to partly fill this gap by characterizing the mode of cytotoxicity of 2,5-diaziridinyl-3,6-dimethyl-1,4-be...

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Detalles Bibliográficos
Autores principales: Jarasiene-Burinskaja, Rasa, Alksne, Milda, Bartuskiene, Violeta, Voisniene, Violeta, Burinskij, Jaroslav, Cenas, Narimantas, Bukelskiene, Virginija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379112/
https://www.ncbi.nlm.nih.gov/pubmed/28435434
http://dx.doi.org/10.17179/excli2016-783