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Novel 4-thiazolidinone derivatives as agonists of benzodiazepine receptors: Design, synthesis and pharmacological evaluation

A new series of 4-chloro-N-(2-(substitutedphenyl)-4-oxothiazolidin-3-yl)-2-phenoxybenzamide derivatives were designed, synthesized and biologically evaluated as anticonvulsant agents. The designed compounds have the main essential functional groups for binding to the benzodiazepine receptors and 4-t...

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Detalles Bibliográficos
Autores principales: Faizi, Mehrdad, Jahani, Reza, Ebadi, Seyed Abbas, Tabatabai, Sayyed Abbas, Rezaee, Elham, Lotfaliei, Mehrnaz, Amini, Mohsen, Almasirad, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379113/
https://www.ncbi.nlm.nih.gov/pubmed/28435427
http://dx.doi.org/10.17179/excli2016-692