Dioscin induces demethylation of DAPK-1 and RASSF-1alpha genes via the antioxidant capacity, resulting in apoptosis of bladder cancer T24 cells

DNA methylation at CpG rich regions often occurs at tumor suppressor gene promoters, resulting in reduced gene expression and final carcinogenesis. Hypermethylation of tumor suppressor genes, including DAPK-1 and RASSF-1α genes, have been found in patients with bladder carcinoma (BC) in some western...

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Detalles Bibliográficos
Autores principales: Zhou, Qiang, Song, Wei, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379114/
https://www.ncbi.nlm.nih.gov/pubmed/28435431
http://dx.doi.org/10.17179/excli2016-571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379114/
https://www.ncbi.nlm.nih.gov/pubmed/28435431
http://dx.doi.org/10.17179/excli2016-571

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