Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells

BACKGROUND: Human polypyrimidine tract binding protein 3 (PTBP3) was first discovered in 1999 and has been well characterised as a differentiation regulator. However, its role in human cancer has rarely been reported. Our previous study revealed increased PTBP3 protein level in gastric cancer tissue...

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Detalles Bibliográficos
Autores principales: Liang, Xin, Shi, Haiyang, Yang, Liyan, Qiu, Cen, Lin, Shengchao, Qi, Yingxue, Li, Jiyu, Zhao, Aiguang, Liu, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379144/
https://www.ncbi.nlm.nih.gov/pubmed/28222070
http://dx.doi.org/10.1038/bjc.2017.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379144/
https://www.ncbi.nlm.nih.gov/pubmed/28222070
http://dx.doi.org/10.1038/bjc.2017.32

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