Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer

BACKGROUND: Activating mutations in KRAS have been suggested as potential predictive and prognostic biomarkers. However, the prognostic impact of specific point mutations remains less clear. This study assessed the prognostic impact of specific KRAS mutations on survival for patients with colorectal...

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Detalles Bibliográficos
Autores principales: Jones, Robert P, Sutton, Paul A, Evans, Jonathan P, Clifford, Rachel, McAvoy, Andrew, Lewis, James, Rousseau, Abigail, Mountford, Roger, McWhirter, Derek, Malik, Hassan Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379149/
https://www.ncbi.nlm.nih.gov/pubmed/28208157
http://dx.doi.org/10.1038/bjc.2017.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379149/
https://www.ncbi.nlm.nih.gov/pubmed/28208157
http://dx.doi.org/10.1038/bjc.2017.37

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