Oncogenic role of PDK4 in human colon cancer cells

BACKGROUND: Cancer cells maintain high rates of glycolysis. Pyruvate dehydrogenase kinases (PDK) contribute to this phenomenon, which favours apoptosis resistance and cellular transformation. We previously reported upregulation of PDK4 in normal mucosa of colorectal cancer (CRC) patients compared wi...

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Detalles Bibliográficos
Autores principales: Leclerc, D, Pham, D N T, Lévesque, N, Truongcao, M, Foulkes, W D, Sapienza, C, Rozen, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379150/
https://www.ncbi.nlm.nih.gov/pubmed/28208156
http://dx.doi.org/10.1038/bjc.2017.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379150/
https://www.ncbi.nlm.nih.gov/pubmed/28208156
http://dx.doi.org/10.1038/bjc.2017.38

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