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Oncogenic role of PDK4 in human colon cancer cells
BACKGROUND: Cancer cells maintain high rates of glycolysis. Pyruvate dehydrogenase kinases (PDK) contribute to this phenomenon, which favours apoptosis resistance and cellular transformation. We previously reported upregulation of PDK4 in normal mucosa of colorectal cancer (CRC) patients compared wi...
Autores principales: | Leclerc, D, Pham, D N T, Lévesque, N, Truongcao, M, Foulkes, W D, Sapienza, C, Rozen, R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379150/ https://www.ncbi.nlm.nih.gov/pubmed/28208156 http://dx.doi.org/10.1038/bjc.2017.38 |
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