Nucleotide Dependent Switching in Rho GTPase: Conformational Heterogeneity and Competing Molecular Interactions

Ras superfamily of GTPases regulate myriad cellular processes through a conserved nucleotide (GTP/GDP) dependent switching mechanism. Unlike Ras family of GTPases, for the Rho GTPases, there is no clear evidence for the existence of “sub-states” such as state 1 & state 2 in the GTP bound form. T...

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Detalles Bibliográficos
Autores principales: Kumawat, Amit, Chakrabarty, Suman, Kulkarni, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379185/
https://www.ncbi.nlm.nih.gov/pubmed/28374773
http://dx.doi.org/10.1038/srep45829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379185/
https://www.ncbi.nlm.nih.gov/pubmed/28374773
http://dx.doi.org/10.1038/srep45829

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