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Pathogen recognition of a novel C-type lectin from Marsupenaeus japonicus reveals the divergent sugar-binding specificity of QAP motif

C-type lectins (CTLs) are calcium-dependent carbohydrate-binding proteins known to assist the innate immune system as pattern recognition receptors (PRRs). The binding specificity of CTLs lies in the motif of their carbohydrate recognition domain (CRD), the tripeptide motifs EPN and QPD bind to mann...

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Detalles Bibliográficos
Autores principales: Alenton, Rod Russel R., Koiwai, Keiichiro, Miyaguchi, Kohei, Kondo, Hidehiro, Hirono, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379193/
https://www.ncbi.nlm.nih.gov/pubmed/28374848
http://dx.doi.org/10.1038/srep45818